A closer look at dosing with ITVISMA. Lab tests and administration of oral corticosteroids are required before and after injection. Andrew lives with SMA and hasn't received ITVISMA. Individuals shown were compensated for their time.

ITVISMA is a treatment with no refills, no recurring injections, and no ongoing reauthorizations.* Just one dose designed to work continuously.

Dosing across spinal muscular atrophy (SMA) treatments for people 2 years of age and older^†

Treatment	ITVISMA	SPINRAZA^®(nusinersen)	EVRYSDI^®(risdiplam)
Dosing schedule	A single dose	3x per year (after initial starting doses)	Once daily
How it's given	Injected into spine (intrathecal injection)	Injected into spine (intrathecal injection)	Orally as liquid or tablet

Be sure to talk to a doctor about detailed dosing information.

Picture what life could look like with a one-time dose of ITVISMA.

See the study results See how it works

*Corticosteroids are required before and after treatment and may be administered orally (which may require refills and reauthorization) or via injection if oral corticosteroids are not tolerated or effective. Talk to your doctor.
^†This chart is intended to show dosing information only and should not be considered a comparison of efficacy or safety.
EVRYSDI^® is a registered trademark of Genentech USA, Inc.
SPINRAZA^® is a registered trademark of Biogen.

Picture what life could look like with a one-time dose of ITVISMA.

IMPORTANT SAFETY INFORMATION

INDICATION